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Welcome to the Li Lab, where you can learn more about who we are and what we do in our research. We are interested in functional nucleic acids, specifically DNAzymes (DNA-based enzymes) and ribozymes (RNA-based enzymes), aptamers (DNA and RNA molecules that bind a target of interest), riboswitches (RNA molecules that regulate gene expression in cells in response to the concentration of a specific metabolite), and small bacterial non-coding RNAs. Our work spans the disciplines of biochemistry, chemical biology, molecular biology, nucleic acids research, bioanalytical chemistry and nanotechnology.